Article
Visualization of novel simian virus 40 DNA recombination intermediates induced by ultraviolet light irradiation.
Nucleic acids research - 1 Dec 1991
Hsu M T
Abstract excerpt
Electron microscopic technique was used to examine the structures of SV40 DNA recombination intermediates induced by ultraviolet irradiation as an approach for understanding recombination mechanisms in animal cells. Putative recombination intermediate with the characteristic Holliday junction was observed in both SV40 and CV-1 monkey kidney cell DNA. These results suggest that Holliday recombination intermediate...
Topics
- Animals
- Cell Line
- DNA Replication
- DNA, Circular
- DNA, Viral
- Haplorhini
- Microscopy, Electron
- Mutation
- Nucleic Acid Conformation
- Recombination, Genetic
- Simian virus 40
- Ultraviolet Rays
