Article
A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDa.
Malaria journal - 20 Apr 2006
Takala Shannon L, Smith David L, Stine O Colin, Coulibaly Drissa, Thera Mahamadou A, Doumbo Ogobara K, Plowe Christopher V
Abstract excerpt
BACKGROUND: Malaria vaccine efficacy may be compromised if the frequency of non-target alleles increases following vaccination with a genetically polymorphic target. Methods are needed to monitor genetic diversity in polymorphic vaccine antigens, but determining which genetic variants of such ant...
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