CLINICAL COUNTERPOINT: The Physiology of Placental Lactogen in Human Pregnancy*

Abstract excerpt

In summary, current evidence strongly suggests that PL may play a pivotal role during pregnancy, acting through distinct PL receptors to regulate and coordinate growth and metabolism in the mother and fetus. In early and midgestation, PL may be secreted preferentially into the fetal circulation, exerting growth-promoting effects at a time when the rate of linear growth of the fetus is maximal. Subsequently,...

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