Article
Reduced galectin-3 expression is an indicator of unfavorable prognosis in gastric cancer.
Anticancer research - 1 Jan 2000
Okada Kohji, Shimura Tatsuo, Suehiro Taketoshi, Mochiki Erito, Kuwano Hiroyuki
Abstract excerpt
BACKGROUND: Galectin-3 (gal-3) participates in a variety of biological events, including cell adhesion, proliferation, differentiation and apoptosis. The aim of this study was to determine the relationship of gal-3 expression with clinicopathological findings and prognosis in patients with gastric cancer. PATIENTS AND METHODS: Gal-3 and Ki-67 expressions were assessed by immunohistochemistry in 115 patients with...
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