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Article

Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Apr 2006

Hashibe Mia, Boffetta Paolo, Zaridze David, Shangina Oxana, Szeszenia-Dabrowska Neonila, Mates Dana, Janout Vladimir, Fabiánová Eleonóra, Bencko Vladimir, Moullan Norman, Chabrier Amelie, Hung Rayjean, Hall Janet, Canzian Federico, Brennan Paul

Abstract excerpt

BACKGROUND: Incidence and mortality rates of upper aerodigestive tract cancers in Central Europe are among the highest in the world and have increased substantially in recent years. This increase is likely to be due to patterns of alcohol and tobacco consumption. Genetic susceptibility to upper aerodigestive tract cancer in relation to such exposures is an important aspect that should be investigated among...

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Alcohol Dehydrogenase
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial
Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Europe, Eastern

Head and Neck Neoplasms

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Identifiers

PMID: 16614111
DOI: 10.1158/1055-9965.EPI-05-0710

Genes

ALDH2

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Evidence for an important role of alcohol- and aldehyde-metabolizing genes in cancers of the upper aerodigestive tract.PMID 16614111Read ↗

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Alcohol Consumption, ALDH2 Polymorphism as Risk Factors for Upper Aerodigestive Tract Cancer Progression and PrognosisSemantic proximity Read ↗

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