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Article

The v-MFG test: investigating maternal, offspring and maternal-fetal genetic incompatibility effects on disease and viability.

Genetic epidemiology - 1 May 2006

Hsieh Hsin-Ju, Palmer Christina G S, Harney Sinead, Newton Julia L, Wordsworth Paul, Brown Matthew A, Sinsheimer Janet S

Abstract excerpt

The MFG test is a family-based association test that detects genetic effects contributing to disease in offspring, including offspring allelic effects, maternal allelic effects and MFG incompatibility effects. Like many other family-based association tests, it assumes that the offspring survival and the offspring-parent genotypes are conditionally independent provided the offspring is affected. However, when the...

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PMID: 16607625
DOI: 10.1002/gepi.20148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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