Article
Human bone marrow-derived stem cells acquire epithelial characteristics through fusion with gastrointestinal epithelial cells.
PloS one - 5 May 2011
Ferrand Jonathan, Noël Danièle, Lehours Philippe, Prochazkova-Carlotti Martina, Chambonnier Lucie, Ménard Armelle, Mégraud Francis, Varon Christine
Abstract excerpt
Bone marrow-derived mesenchymal stem cells (MSC) have the ability to differentiate into a variety of cell types and are a potential source for epithelial tissue repair. Several studies have demonstrated their ability to repopulate the gastrointestinal tract (GIT) in bone marrow transplanted patients or in animal models of gastrointestinal carcinogenesis where they were the source of epithelial cancers. However,...
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