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Article

Imbalanced distribution of Plasmodium falciparum EBA-175 genotypes related to clinical status in children from Bakoumba, Gabon.

Clinical medicine & research - 1 Mar 2006

Touré Fousseyni S, Bisseye C, Mavoungou Elie

Abstract excerpt

OBJECTIVE: The erythrocyte binding antigen 175 kDa (EBA-175) of Plasmodium falciparum is one of the major ligands for red blood cell invasion by merozoites. EBA-175 is a dimorphic antigen but the role that dimorphism plays in host parasite interaction is not fully understood. In this study, we sought to determine the distribution of EBA-175 genotypes and its pathogenetic influence. METHODS: The nested polymerase...

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Identifiers

PMID: 16595788
DOI: 10.3121/cmr.4.1.7
PMCID: PMC1435655

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CAMP

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