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Article

Extracellular matrix in disc degeneration.

The Journal of bone and joint surgery. American volume - 1 Apr 2006

Feng Haoyu, Danfelter Mikael, Strömqvist Björn, Heinegård Dick

Abstract excerpt

The extracellular matrix of the intervertebral disc structures contains many molecules also found in cartilage. The extremely polyanionic proteoglycans play a central role, particularly in the nucleus, by creating an osmotic environment leading to retention of water and ensuing resistance to deformation-important for the resilience of the tissue. Another major structural entity particularly important in the...

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Identifiers

PMID: 16595439
DOI: 10.2106/JBJS.E.01341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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