[Butyrylcholinesterase deficiency: how to analyse the cholinesterase activity in small children?].

doi:10.1016/j.annfar.2006.02.009

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Article

[Butyrylcholinesterase deficiency: how to analyse the cholinesterase activity in small children?].

Annales francaises d'anesthesie et de reanimation - 1 Jun 2006

Lejus C, Delaroche O, Trille E, Blanloeil Y, Pinaud M

Abstract excerpt

We report the case of a prolonged neuromuscular blockade in an 18-month-old age girl following administration of a usual dose of succinylcholine. The diagnosis was highly suggested by the clinical history while cholinesterase activity was included in adult normal values but below values of a personal series of 41 small children. The familial analysis of dibucaine and fluoride number confirmed the hypothesis of an...

Topics

Age Factors
Anesthetics, Local
Butyrylcholinesterase
Cholinesterases
Dibucaine
Female
Genetic Variation
Humans
Infant
Neuromuscular Blockade
Neuromuscular Depolarizing Agents
Phenotype
Succinylcholine

Source

Open in PubMed

Identifiers

PMID: 16581221
DOI: 10.1016/j.annfar.2006.02.009

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