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Article

Imprinting disruption of the <i>CDKN1C</i>/<i>KCNQ1OT1</i> domain: the molecular mechanisms causing Beckwith-Wiedemann syndrome and cancer

1 Jan 2006

Abstract excerpt

Human chromosomal region 11p15.5, which is homologous to mouse chromosome region 7F5, is a well-known imprinted region. The <i>CDKN1C/KCNQ1OT1</i> imprinted domain, which is one of two imprinted domains at 11p15.5, includes nine imprinted genes regulated by an imprinting center (IC). The <i>CDKN1C/KCNQ1OT1</i> IC is a differentially methylated region of...

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PMID: 16575194
DOI: 10.1159/000090846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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