Article
Adult Paget's disease of bone: a review.
Rheumatology (Oxford, England) - 1 Dec 2017
Paul Tuck Stephen, Layfield Robert, Walker Julie, Mekkayil Babitha, Francis Roger
Abstract excerpt
Adult PD of bone is the second commonest metabolic bone condition after osteoporosis. The condition is characterized by increased bone cell activity, with bone-resorbing osteoclasts often larger and containing more nuclei than normal, and osteoblasts producing increased amounts of disorganized bone. This leads to expanded bone of poor quality possessing both sclerotic and lytic areas. PD of bone has a strong...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.