Article
Arenavirus diversity and evolution: quasispecies in vivo.
Current topics in microbiology and immunology - 1 Jan 2006
Sevilla N, de la Torre J C
Abstract excerpt
Arenaviruses exist as viral quasispecies due to the high mutation rates of the low-fidelity viral RNA-dependent RNA polymerase (RdRp). This genomic heterogeneity is advantageous to the population, allowing for adaptation to rapidly changing environments that present varying types and degrees of selective pressure. The significant variation in biological properties observed among lymphocytic choriomeningitis virus...
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