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Article

Arenavirus Variations Due to Host-Specific Adaptation

17 Jan 2013

Abstract excerpt

Arenavirus particles are enveloped and contain two single-strand RNA genomic segments with ambisense coding. Genetic plasticity of the arenaviruses comes from transcription errors, segment reassortment, and permissive genomic packaging, and results in their remarkable ability, as a group, to infect a wide variety of hosts. In this review, we discuss some in vitro studies of virus genetic and phenotypic variation...

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PMID: 23344562
DOI: 10.3390/v5010241

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