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Article

Adult chicken alpha-globin gene expression in transfected QT6 quail cells: evidence for a negative regulatory element in the alpha D gene region.

Nucleic acids research - 11 Oct 1991

Lewis W, Lee J D, Dodgson J B

Abstract excerpt

The chicken adult alpha-globin genes, alpha A and alpha D, are closely linked in chromosomal DNA and are coordinately expressed in vivo in an approximate 3:1 ratio, respectively. When subcloned DNAs containing one or the other gene are stably transfected into QT6 quail fibroblasts, the alpha A-globin gene is expressed at measurable RNA levels, but the alpha D gene is not. The alpha A gene expression can be...

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Identifiers

PMID: 1656392
DOI: 10.1093/nar/19.19.5321
PMCID: PMC328894

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