Adult chicken alpha-globin gene expression in transfected QT6 quail cells: evidence for a negative regulatory element in the alpha D gene region.

doi:10.1093/nar/19.19.5321

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Article

Adult chicken alpha-globin gene expression in transfected QT6 quail cells: evidence for a negative regulatory element in the alpha D gene region.

Nucleic acids research - 11 Oct 1991

Lewis W, Lee J D, Dodgson J B

Abstract excerpt

The chicken adult alpha-globin genes, alpha A and alpha D, are closely linked in chromosomal DNA and are coordinately expressed in vivo in an approximate 3:1 ratio, respectively. When subcloned DNAs containing one or the other gene are stably transfected into QT6 quail fibroblasts, the alpha A-gl...

Topics

Animals
Avian Sarcoma Viruses
Base Sequence
Cell Line
Chickens
Cloning, Molecular
Enhancer Elements, Genetic
Gene Expression Regulation
Globins
HeLa Cells
Humans
Molecular Sequence Data
Multigene Family
Mutation
Promoter Regions, Genetic
Regulatory Sequences, Nucleic Acid
Repetitive Sequences, Nucleic Acid
Restriction Mapping

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Identifiers

PMID: 1656392
DOI: 10.1093/nar/19.19.5321
PMCID: PMC328894

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1656392-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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