Article
Spontaneous and therapeutic abortions and the risk of breast cancer among BRCA mutation carriers.
Breast cancer research : BCR - 1 Jan 2006
Friedman Eitan, Kotsopoulos Joanne, Lubinski Jan, Lynch Henry T, Ghadirian Parviz, Neuhausen Susan L, Isaacs Claudine, Weber Barbara, Foulkes William D, Moller Pal, Rosen Barry, Kim-Sing Charmaine, Gershoni-Baruch Ruth, Ainsworth Peter, Daly Mary, Tung Nadine, Eisen Andrea, Olopade Olufunmilayo I, Karlan Beth, Saal Howard M, Garber Judy E, Rennert Gad, Gilchrist Dawna, Eng Charis, Offit Kenneth, Osborne Michael, Sun Ping, Narod Steven A
Abstract excerpt
INTRODUCTION: BRCA1 and BRCA2 mutation carriers are at increased risk for developing both breast and ovarian cancer. It has been suggested that carriers of BRCA1/2 mutations may also be at increased risk of having recurrent (three or more) miscarriages. Several reproductive factors have been shown to influence the risk of breast cancer in mutation carriers, but the effects of spontaneous and therapeutic abortions...
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