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Article

Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Nov 1991

Dumont M E, Cardillo T S, Hayes M K, Sherman F

Abstract excerpt

Heme is covalently attached to cytochrome c by the enzyme cytochrome c heme lyase. To test whether heme attachment is required for import of cytochrome c into mitochondria in vivo, antibodies to cytochrome c have been used to assay the distributions of apo- and holocytochromes c in the cytoplasm and mitochondria from various strains of the yeast Saccharomyces cerevisiae. Strains lacking heme lyase accumulate...

Topics

Apoproteins
Base Sequence
Codon
Cytochrome c Group
Cytochromes c
Genotype
Intracellular Membranes
Kinetics
Lyases
Mitochondria
Models, Biological
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutagenesis, Site-Directed

Oligonucleotides

Restriction Mapping

Saccharomyces cerevisiae

Submitochondrial Particles

Source

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Identifiers

PMID: 1656231
DOI: 10.1128/mcb.11.11.5487-5496.1991
PMCID: PMC361918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1656231-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Role of cytochrome c heme lyase in mitochondrial import and accumulation of cytochrome c in Saccharomyces cerevisiae.PMID 1656231Read ↗

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