Article
Genes in the polyamine biosynthesis pathway may be involved in prostate cancer susceptibility.
Future oncology (London, England) - 1 Oct 2005
Zeegers Maurice P, Ostrer Harry
Abstract excerpt
One of the most investigated low-penetrance genes is the androgen receptor gene. A recent meta-analysis showed however that the absolute difference in number of repeats between cases and controls was less than one repeat. This result has questioned whether the androgen receptor gene could be functionally important in prostate cancer etiology. The authors hypothesize that genes that are downstream from the...
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