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Article

rpoB mutations conferring rifampicin-resistance affect growth, stress response and motility in Vibrio vulnificus.

Microbiology (Reading, England) - 1 Dec 2020

Cutugno Laura, Mc Cafferty Jennifer, Pané-Farré Jan, O'Byrne Conor, Boyd Aoife

Abstract excerpt

Rifampicin is a broad-spectrum antibiotic that binds to the bacterial RNA polymerase (RNAP), compromising DNA transcription. Rifampicin resistance is common in several microorganisms and it is typically caused by point mutations in the gene encoding the β subunit of RNA polymerase, rpoB. Different rpoB mutations are responsible for various levels of rifampicin resistance and for a range of secondary effects. rpoB...

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Source

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Identifiers

PMID: 33186092
DOI: 10.1099/mic.0.000991
PMCID: PMC7819355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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