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Article

Axonal damage and demyelination in long-term dorsal root ganglia cultures from a rat model of Charcot-Marie-Tooth type 1A disease.

The European journal of neuroscience - 1 Mar 2006

Nobbio Lucilla, Gherardi Gianfranco, Vigo Tiziana, Passalacqua Mario, Melloni Edon, Abbruzzese Michele, Mancardi Gianluigi, Nave Klaus-Armin, Schenone Angelo

Abstract excerpt

Clinical progression in hereditary and acquired demyelinating disorders of both the central and peripheral nervous system is mainly due to a time-dependent axonal impairment. We established 90-day dorsal root ganglia (DRG) cultures from a rat model of Charcot-Marie-Tooth type 1A (CMT1A) neuropathy to evaluate the structure of myelin and axons, and the expression of myelin-related proteins and cytoskeletal...

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Identifiers

PMID: 16553608
DOI: 10.1111/j.1460-9568.2006.04666.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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