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Article

Neurogenin1 is a determinant of zebrafish basal forebrain dopaminergic neurons and is regulated by the conserved zinc finger protein Tof/Fezl.

Proceedings of the National Academy of Sciences of the United States of America - 28 Mar 2006

Jeong Jae-Yeon, Einhorn Zev, Mercurio Sara, Lee Susie, Lau Billy, Mione Marina, Wilson Stephen W, Guo Su

Abstract excerpt

The development of vertebrate basal forebrain dopaminergic (DA) neurons requires the conserved zinc finger protein Too Few (Tof/Fezl) in zebrafish. However, how Tof/Fezl regulates the commitment and differentiation of these DA neurons is not known. Proneural genes encoding basic helix-loop-helix transcription factors regulate the development of multiple neuronal lineages, but their involvement in vertebrate DA...

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Identifiers

PMID: 16549779
DOI: 10.1073/pnas.0600337103
PMCID: PMC1458808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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