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Article

The pathophysiology of traumatic brain injury in alpha7 nicotinic cholinergic receptor knockout mice.

Brain research - 14 Apr 2006

Kelso Matthew L, Wehner Jeanne M, Collins Allan C, Scheff Stephen W, Pauly James R

Abstract excerpt

The alpha7 nicotinic cholinergic receptor is a ligand-gated ion channel with calcium permeability similar to that of ionotrophic glutamate receptors. Previous studies from our laboratory have implicated changes in expression alpha7 nicotinic cholinergic receptors in the pathophysiology of traumatic brain injury (TBI). In rats, TBI causes a time-dependent and significant decrease in cortical and hippocampal...

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Identifiers

PMID: 16545784
DOI: 10.1016/j.brainres.2006.01.127

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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