Article
Interaction of serotonergic and noradrenergic gene variants in panic disorder.
Psychiatric genetics - 1 Apr 2006
Freitag Christine M, Domschke Katharina, Rothe Claudia, Lee Yoo-Jeong, Hohoff Christa, Gutknecht Lise, Sand Philipp, Fimmers Rolf, Lesch Klaus-Peter, Deckert Jürgen
Abstract excerpt
OBJECTIVE: Panic disorder is an anxiety disorder with an estimated heritability of 48%. Associations findings have been obtained with candidate genes from both serotonergic and noradrenergic pathways including regulatory and coding variants of the serotonin receptor 1A gene, the monoamine oxidase A gene, the catechol-O-methyltransferase gene and the norepinephrine transporter gene. METHODS: In the present study,...
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