Article
Mitochondrial DNA in the sea urchin Arbacia lixula: nucleotide sequence differences between two polymorphic molecules indicate asymmetry of mutations.
Gene - 22 Jul 1991
De Giorgi C, De Luca F, Saccone C
Abstract excerpt
Two polymorphic forms of mitochondrial DNA (mtDNA) extracted from Arbacia lixula eggs were cloned and the nucleotide sequences of specific regions determined. A comparison of the sequences of the sense strand of the two molecules demonstrates that all the differences are transitions and only of the A----G type. A change such as G----A (or A----G) on the sense mtDNA strand results from either a direct G----A (or...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Replication
- DNA, Mitochondrial
- Electron Transport Complex IV
- Mathematics
- Mitochondria
- Molecular Sequence Data
- Mutation