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Article

Genetic mapping of the beta 1 GABA receptor gene to human chromosome 4, using a tetranucleotide repeat polymorphism.

American journal of human genetics - 1 Sept 1991

Dean M, Lucas-Derse S, Bolos A, O'Brien S J, Kirkness E F, Fraser C M, Goldman D

Abstract excerpt

As more coding loci for functional human genes are described, there is a growing need to identify DNA polymorphisms in specific genes. By examining DNA sequences within the introns of the beta 1 subunit of the gamma-aminobutyric acid receptor gene, GABARB1, we found a tetranucleotide repeat sequence (GATA). Amplification of this region by using PCR revealed seven alleles and a high degree of polymorphism (PIC =...

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 4
Cloning, Molecular
DNA, Satellite
Female
Genetic Linkage
Humans
Introns
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Receptors, GABA-A

Repetitive Sequences, Nucleic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 1652891
PMCID: PMC1683131

Genes

ALB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1652891-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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