Article
Genetic mapping of the beta 1 GABA receptor gene to human chromosome 4, using a tetranucleotide repeat polymorphism.
American journal of human genetics - 1 Sept 1991
Dean M, Lucas-Derse S, Bolos A, O'Brien S J, Kirkness E F, Fraser C M, Goldman D
Abstract excerpt
As more coding loci for functional human genes are described, there is a growing need to identify DNA polymorphisms in specific genes. By examining DNA sequences within the introns of the beta 1 subunit of the gamma-aminobutyric acid receptor gene, GABARB1, we found a tetranucleotide repeat sequence (GATA). Amplification of this region by using PCR revealed seven alleles and a high degree of polymorphism (PIC =...
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