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Article

Sensitization of IL-2 signaling through TLR-7 enhances B lymphoma cell immunogenicity.

Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2006

Tomic Jelena, White Dionne, Shi Yonghong, Mena Jenny, Hammond Caitlin, He Liwei, Miller Richard L, Spaner David E

Abstract excerpt

The innate ability of B lymphoma cells to escape control by tumor-reactive T cells must be overcome to develop effective immunotherapies for these diseases. Because signals from both the innate and adaptive immune systems direct the acquisition of strong immunogenicity by professional APCs, the effects of IL-2 and the TLR-7 agonist, S28690, on the immunogenic properties of chronic lymphocytic leukemia (CLL) B...

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Share to Interleukin-2
Share to Lymphoma, B-Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16517754
DOI: 10.4049/jimmunol.176.6.3830

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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