Article
Use of amnion and placenta in neonatal screening for canine GM1-gangliosidosis and the risk of diagnostic misclassifications.
Veterinary clinical pathology - 1 Mar 2006
Yamato Osamu, Jo Eun-Og, Satoh Hiroyuki, Yamauchi Toyofumi, Kobayashi Asogi, Yamasaki Masahiro, Maede Yoshimitsu
Abstract excerpt
BACKGROUND: A closed breeding colony of Shiba dogs with GM1-gangliosidosis is maintained at Hokkaido University (Sapporo, Japan). Neonatal genotyping is essential to control the breeding colony genetically as an animal model for the human disease. OBJECTIVES: The purpose of the present study was to determine the utility of amnion and placenta in the neonatal screening or diagnosis for canine GM1-gangliosidosis....
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