Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Apr 2006

Blasi Francesca, Bacchelli Elena, Pesaresi Giulia, Carone Simona, Bailey Anthony J, Maestrini Elena

Abstract excerpt

Neuroligin abnormalities have been recently implicated in the aetiology of autism spectrum disorders (ASD), given the finding of point mutations in the two X-linked genes NLGN3 and NLGN4X and the important role of neuroligins in synaptogenesis. To enquire on the relevance and frequency of neuroli...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autistic Disorder
Share to Carrier Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Adhesion Molecules, Neuronal

Share to Chromosomes, Human, X

Share to International Cooperation

Share to Mutation, Missense

Share to Nerve Tissue Proteins

Share to Registries

Source

Identifiers

PMID: 16508939
DOI: 10.1002/ajmg.b.30287

Genes

NLGN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16508939-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Absence of coding mutations in the X-linked genes neuroligin 3 and neuroligin 4 in individuals with autism from the IMGSAC collection.PMID 16508939Read ↗

Mutation screening of X-chromosomal neuroligin genes: no mutations in 196 autism probands.Semantic proximity Read ↗

Analysis of four neuroligin genes as candidates for autism.Semantic proximity Read ↗

Not all neuroligin 3 and 4X missense variants lead to significant functional inactivation.Semantic proximity Read ↗

Variations analysis of NLGN3 and NLGN4X gene in Chinese autism patients.Semantic proximity Read ↗

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.Semantic proximity Read ↗

A substitution involving the NLGN4 gene associated with autistic behavior in the Greek population.Semantic proximity Read ↗

Analysis of the genes encoding neuroligins NLGN3 and NLGN4 in Bulgarian patients with autism.Semantic proximity Read ↗

Association Analysis of Noncoding Variants in Neuroligins 3 and 4X Genes with Autism Spectrum Disorder in an Italian Cohort.Semantic proximity Read ↗

Mutation screening in the Greek population and evaluation of NLGN3 and NLGN4X genes causal factors for autism.Semantic proximity Read ↗

A sex-specific association of common variants of neuroligin genes (NLGN3 and NLGN4X) with autism spectrum disorders in a Chinese Han cohort.Semantic proximity Read ↗

Case Report-An Inherited Loss-of-Function NRXN3 Variant Potentially Causes a Neurodevelopmental Disorder with Autism Consistent with Previously Described 14q24.3-31.1 Deletions.Semantic proximity Read ↗

NLGN3/NLGN4 gene mutations are not responsible for autism in the Quebec population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.