Article
Luteinizing hormone modulates cognition and amyloid-beta deposition in Alzheimer APP transgenic mice.
Biochimica et biophysica acta - 1 Apr 2006
Casadesus Gemma, Webber Kate M, Atwood Craig S, Pappolla Miguel A, Perry George, Bowen Richard L, Smith Mark A
Abstract excerpt
Until recently, the study of hormonal influences in Alzheimer disease was limited to the role of sex steroids. Despite numerous epidemiological studies supporting a protective role for estrogen in Alzheimer disease, recent studies show that estrogen administration in elderly women increases the risk of disease. Reconciling these contradictory reports, we previously hypothesized that other hormones of the...
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