Article
Expression of Growth Differentiation Factor-9 Messenger Ribonucleic Acid in Ovarian and Nonovarian Rodent and Human Tissues*
1 May 1998
Abstract excerpt
Growth differentiation factor-9 (GDF-9) is a member of the transforming growth factor-beta family that is reported to be expressed exclusively in the ovary, specifically in the oocyte. Female mice deficient in GDF-9 are infertile, suggesting that GDF-9 receptor agonists and antagonists may specifically modulate fertility. We now report that GDF-9 messenger RNA (mRNA) is expressed in nonovarian tissues in mice,...
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