Article
Association analysis of genes in the renin-angiotensin system with subclinical cardiovascular disease in families with Type 2 diabetes mellitus: the Diabetes Heart Study.
Diabetic medicine : a journal of the British Diabetic Association - 1 Mar 2006
Burdon K P, Langefeld C D, Wagenknecht L E, Carr J J, Freedman B I, Herrington D, Bowden D W
Abstract excerpt
AIMS: Cardiovascular disease (CVD) is a major complication of Type 2 diabetes mellitus. The renin-angiotensin system (RAS) and nitric oxide production are both important regulators of vascular function and blood pressure. Genes encoding proteins involved in these pathways are candidates for a contribution to CVD in diabetic patients. We have investigated variants of the angiotensinogen (AGT), angiotensin...
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