ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex.

doi:10.1002/j.1460-2075.1991.tb07732.x

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Article

ABC1, a novel yeast nuclear gene has a dual function in mitochondria: it suppresses a cytochrome b mRNA translation defect and is essential for the electron transfer in the bc 1 complex.

The EMBO journal - 1 Aug 1991

Bousquet I, Dujardin G, Slonimski P P

Abstract excerpt

We have cloned and sequenced a novel yeast nuclear gene ABC1 which suppresses, in multicopy, the cytochrome b mRNA translation defect due to the nuclear mutation cbs2-223. Analysis of the ABC1 gene shows that it is weakly expressed, it could code for a protein of 501 amino acids which has a typical presequence of a protein imported into mitochondria and which does not display a strong similarity to any known...

Topics

Amino Acid Sequence
Base Sequence
Cell Nucleus
Chromosomes, Fungal
Cytochrome b Group
Electron Transport
Electron Transport Complex III
Genes, Fungal
Mitochondria
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Nucleic Acid Hybridization

Protein Biosynthesis

RNA, Messenger

Restriction Mapping

Saccharomyces cerevisiae

Source

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Identifiers

PMID: 1648478
DOI: 10.1002/j.1460-2075.1991.tb07732.x
PMCID: PMC452883

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1648478-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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