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Article

Rad52 depletion in Candida albicans triggers both the DNA-damage checkpoint and filamentation accompanied by but independent of expression of hypha-specific genes.

Molecular microbiology - 1 Mar 2006

Andaluz Encarnación, Ciudad Toni, Gómez-Raja Jonathan, Calderone Richard, Larriba Germán

Abstract excerpt

We have analysed the effect of RAD52 deletion in several aspects of the cell biology of Candida albicans. Cultures of rad52Delta strains exhibited slow growth and contained abundant cells with a filamentous morphology. Filamentation with polarization of actin patches was accompanied by the induction of the hypha-specific genes (HSG) ECE1, HWP1 and HGC1. However, filament formation occurred in the absence of the...

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Source

Identifiers

PMID: 16468988
DOI: 10.1111/j.1365-2958.2005.05038.x

Genes

ECE1
RAD52

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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