Article
Neonatal susceptibility to UV induced cutaneous malignant melanoma in a mouse model.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology - 1 Feb 2006
Wolnicka-Glubisz Agnieszka, Noonan Frances P
Abstract excerpt
UV irradiation has multiple effects on skin including erythema, immunosuppression and the induction of keratinocyte-derived skin cancers and cutaneous malignant melanoma (CMM). CMM which arises from damage to the melanocyte, the pigment cell of the skin, is associated in epidemiologic studies with sun-exposure of susceptible populations, especially children. Our experimental studies have supported the concept...
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