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Article

Genetic predisposition syndromes: when should they be considered in the work-up of MDS?

Best practice & research. Clinical haematology - 1 Mar 2015

Babushok Daria V, Bessler Monica

Abstract excerpt

Myelodysplastic syndromes (MDS) are clonal hematopoietic disorders characterized by cytopenias, ineffective hematopoiesis, myelodysplasia, and an increased risk of acute myeloid leukemia (AML). While sporadic MDS is primarily a disease of the elderly, MDS in children and young and middle-aged adults is frequently associated with underlying genetic predisposition syndromes. In addition to the classic hereditary...

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Identifiers

PMID: 25659730
DOI: 10.1016/j.beha.2014.11.004
PMCID: PMC4323616

Genes

GATA2
RUNX1
SRP72

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