Article
Evaluation of the CombiChip Mycobacteria Drug-Resistance detection DNA chip for identifying mutations associated with resistance to isoniazid and rifampin in Mycobacterium tuberculosis.
Diagnostic microbiology and infectious disease - 1 Mar 2006
Kim Soo-Young, Park Yeon-Joon, Song Eunsil, Jang Hyunjung, Kim Cheolmin, Yoo Jinyoung, Kang Seok-Jin
Abstract excerpt
The CombiChip Mycobacteriatrade mark Drug-Resistance Detection DNA chip, recently developed by GeneIn (Pusan, South Korea), is an oligonucleotide microchip coupled with polymerase chain reaction for the detection of mutations associated with resistance to isoniazid (INH) and rifampin (RIF). This oligonucleotide chip was compared with DNA sequencing and phenotypic drug susceptibility testing with 69 INH- and/or...
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