HOX genes: seductive science, mysterious mechanisms.

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Article

HOX genes: seductive science, mysterious mechanisms.

The Ulster medical journal - 1 Jan 2006

Lappin Terence R J, Grier David G, Thompson Alexander, Halliday Henry L

Abstract excerpt

HOX genes are evolutionarily highly conserved. The HOX proteins which they encode are master regulators of embryonic development and continue to be expressed throughout postnatal life. The 39 human HOX genes are located in four clusters (A-D) on different chromosomes at 7p15, 17q21 [corrected] 12q13, and 2q31 respectively and are assumed to have arisen by duplication and divergence from a primordial homeobox...

Topics

Animals
Gene Expression Regulation, Developmental
Genes, Homeobox
Homeodomain Proteins
Humans
Multigene Family
Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 16457401
PMCID: PMC1891803

Genes

HOXA13
HOXD13

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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