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Article

The efficacy of short tandem repeat polymorphisms versus single-nucleotide polymorphisms for resolving population structure.

BMC genetics - 30 Dec 2005

Kauwe John S K, Bertelsen Sarah, Bierut Laura Jean, Dunn Gerald, Hinrichs Anthony L, Jin Carol H, Suarez Brian K

Abstract excerpt

Accurately resolving population structure in a sample is important for both linkage and association studies. In this study we investigated the power of single-nucleotide polymorphisms (SNPs) in detecting population structure in a sample of 286 unrelated individuals. We varied the number of SNPs to determine how many are required to approach the degree of resolution obtained with the Collaborative Study on the...

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Identifiers

PMID: 16451699
DOI: 10.1186/1471-2156-6-S1-S84
PMCID: PMC1866696

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