Article
Practical population group assignment with selected informative markers: characteristics and properties of Bayesian clustering via STRUCTURE.
Genetic epidemiology - 1 May 2005
Yang Bao-Zhu, Zhao Hongyu, Kranzler Henry R, Gelernter Joel
Abstract excerpt
Population stratification, which is caused by population genetic substructure (PGS), is a critical issue for the design and interpretation of genetic association studies. Methods to address this problem have been devised, but little is known at this point about practical genotyping requirements for resolving PGS based on different marker characteristics. In this report, we seek to (1) identify a small, practical...
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