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GyrA mutations in ciprofloxacin-resistant clinical isolates of Pseudomonas aeruginosa in a Silesian Hospital in Poland.

Polish journal of microbiology - 1 Jan 2005

Wydmuch Zenobia, Skowronek-Ciołek Olga, Cholewa Krzysztof, Mazurek Urszula, Pacha Jerzy, Kepa Małgorzata, Idzik Danuta, Wojtyczka Robert D

Abstract excerpt

Among 73 clinical isolates of Pseudomonas aeruginosa 48 strains were ciprofloxacine (CIP) susceptible and 25 CIP resistant (Minimal inhibitory concentration--MIC>32 microg/ml - 14 strains) or of intermediate susceptibility to CIP (MIC > or = 1,5 - 32 microg/ml - 11 isolates). Mutations in the quinolone-resistance-determining region (QRDR) of gyrA gene were searched in groups of CIP resistant and of intermediate...

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PMID: 16450835

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