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Article

Doxycycline disrupts transthyretin amyloid: evidence from studies in a FAP transgenic mice model.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2006

Cardoso I, Saraiva M J

Abstract excerpt

Familial amyloidotic polyneuropathy is an autosomal dominant disorder mainly characterized by the extracellular deposition of transthyretin, with special involvement of the peripheral nerve. Several animal models have been generated, including transgenic mice carrying the most prevalent TTR mutat...

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Source

Identifiers

PMID: 16449795
DOI: 10.1096/fj.05-4509com

Genes

TTR
FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16449795-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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