Article
Sarcopenia in the Caenorhabditis elegans pharynx correlates with muscle contraction rate over lifespan.
Experimental gerontology - 1 Mar 2006
Chow David K, Glenn Charles F, Johnston Josiah L, Goldberg Ilya G, Wolkow Catherine A
Abstract excerpt
In muscles, sarcopenia, the loss of muscle mass, is the major cause of aging-related functional decline and frailty. Several factors are correlated with sarcopenia during aging, including contraction-related cellular injury, oxidative stress, endocrine changes and reduced regenerative potential. However the involvement of these factors has not been experimentally investigated. Here, we report that...
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