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Article

Caspase activity is downregulated in choriocarcinoma: a cDNA array differential expression study

27 Jan 2006

Abstract excerpt

BACKGROUND: Placental trophoblast can be considered to be pseudomalignant tissue and the pathogenesis of gestational trophoblastic diseases remains to be clarified. AIMS: To examine the role of caspases 8 and 10, identified by differential expression, on trophoblast tumorigenesis. METHODS: cDNA array hybridisation was used to compare gene expression profiles in choriocarcinoma cell lines (JAR, JEG, and BeWo) and...

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PMID: 16443735
DOI: 10.1136/jcp.2005.028027

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