Article
Cellular invasion by Staphylococcus aureus reveals a functional link between focal adhesion kinase and cortactin in integrin-mediated internalisation.
Journal of cell science - 15 May 2005
Agerer Franziska, Lux Sigrid, Michel Antje, Rohde Manfred, Ohlsen Knut, Hauck Christof R
Abstract excerpt
Nosocomial infections by Staphylococcus aureus, a Gram-positive pathogen colonising human skin and mucosal surfaces, are an increasing health care problem. Clinical isolates almost invariably express fibronectin-binding proteins that, by indirectly linking the bacteria with host integrin alpha5beta1, can promote uptake of the microorganisms by eukaryotic cells. Integrin engagement by pathogenic...
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