Article
Cloninger's temperament dimensions and epidermal growth factor A61G polymorphism in Finnish adults.
Genes, brain, and behavior - 1 Feb 2006
Keltikangas-Järvinen L, Puttonen S, Kivimäki M, Rontu R, Lehtimäki T
Abstract excerpt
This study examines a link between human temperament and epidermal growth factor (EGF). There is evidence that dopaminergic neurotransmission in the central nervous system has a role in temperament, especially in novelty seeking. Functional polymorphism in EGF gene has an impact on EGF production, and EGF, in turn, appears to affect the development of midbrain dopaminergic neurons. Epidermal growth factor gene...
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