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Article

Dietary rescue of fumble--a Drosophila model for pantothenate-kinase-associated neurodegeneration.

Journal of inherited metabolic disease - 1 Jan 2005

Yang Y, Wu Z, Kuo Y M, Zhou B

Abstract excerpt

Hallervorden-Spatz syndrome (HSS) is a devastating neurological disease, characterized by iron accumulation in the globus pallidus in the basal ganglia. Most HSS cases are caused by mutations in one of the four human pantothenate kinases (PANK2). This PANK2-caused subgroup of HSS is sometimes referred as PKAN (pantothenate-kinase-associated neurodegeneration). No effective treatment for PKAN or HSS is currently...

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Identifiers

PMID: 16435199
DOI: 10.1007/s10545-005-0200-0

Genes

PANK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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