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Article

Emerging concepts in GPCR function--the influence of cell phenotype on GPCR pharmacology.

Proceedings of the Western Pharmacology Society - 1 Jan 2005

Eglen Richard M

Abstract excerpt

G protein coupled receptors (GPCRs) are an important class of ligand-activated proteins that regulate cellular metabolism. It is now appears that GPCR function is highly dependent upon the cellular environment in which it is expressed. Indeed, the cell phenotype influences several sequelae of GPCR activation, including GPCR oligomerization, G protein coupling, spatial organization of signaling proteins and...

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PMID: 16416655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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