Article
Oxidative stress, sperm survival and fertility control.
Molecular and cellular endocrinology - 16 May 2006
Aitken R John, Baker Mark A
Abstract excerpt
The human spermatozoon is highly susceptible to oxidative stress. This process induces peroxidative damage in the sperm plasma membrane and DNA fragmentation in both the nuclear and mitochondrial genomes. Such stress may arise from a variety of sources including a lack of antioxidant protection, the presence of redox cycling xenobiotics, infiltrating leukocytes and excess reactive oxygen species production by the...
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