Article
Clinical relevance of oxidative stress and sperm chromatin damage in male infertility: an evidence based analysis
1 Oct 2007
Abstract excerpt
Oxidative stress (OS) in the reproductive tract is now a real entity and concern due to the potential harmful effects of high levels of reactive oxygen species (ROS) on sperm number, motility, quality, and function including damage to sperm nuclear DNA. Evaluation of OS related damage to non-functional sperm is highly relevant as intracytoplasmic sperm injection (ICSI) technique, an effective therapy for severe...
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