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Oxidative stress and male reproductive health

1 Jan 2014

Abstract excerpt

One of the major causes of defective sperm function is oxidative stress, which not only disrupts the integrity of sperm DNA but also limits the fertilizing potential of these cells as a result of collateral damage to proteins and lipids in the sperm plasma membrane. The origins of such oxidative stress appear to involve the sperm mitochondria, which have a tendency to generate high levels of superoxide anion as a...

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PMID: 24369131
DOI: 10.4103/1008-682x.122203

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